More than one million Americans are diagnosed with a chronic brain disorder each year, yet treatments for most complex brain disorders are inadequate or even nonexistent. The K. Lisa Yang and Hock E. Tan Center for Molecular Therapeutics in Neuroscience aims to change how we treat brain disorders by developing innovative molecular tools that target dysfunctional genetic, molecular, and anatomical pathways.
The center was established at the McGovern Institute in 2020 through a $28M gift from philanthropist Lisa Yang and MIT alumnus Hock Tan ’75 and is the second research center established by Yang and Tan at MIT.
Research at the center will initially focus on three major lines of investigation: genetic engineering using CRISPR tools, delivery of genetic and molecular cargo across the blood-brain barrier, and the translation of basic research into the clinical setting. The center will serve as a hub for researchers with backgrounds ranging from biological engineering and genetics to computer science and medicine.