Listening to Synapses

Guoping Feng seeks to explain how synaptic dysfunctions contribute to neurodevelopmental and psychiatric diseases, including autism spectrum disorder (ASD) and schizophrenia. He leads research that uses molecular genetics combined with behavioral and electrophysiological methods to study the components of the synapse. Additionally, the lab has leveraged genetic technologies to help map the cellular diversity in the brain—a valuable tool in neuroscience research. Through understanding the molecular, cellular, and circuit changes underlying brain diseases and disorders, the Feng lab hopes to eventually inform new and more effective treatments.

In his current work, Feng is pursuing four lines of research: studying the development and function of synapses, understanding the neurocircuit mechanisms of behavior, exploring synapse and circuit dysfunction in brain disorders, and developing genetic tools for neuroscience.