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Leveraging human brain tissue for basic and translational neuroscience

Tuesday, January 14, 2020 at 1:00 pm McGovern Institute for Brain Research at MIT Singleton Auditorium, 46-3002 43 Vassar Street, Cambridge, MA Join us for an afternoon symposium featuring the following speakers: Sydney Cash | Massachusetts General Hospital Human Brain Tissue in the Laboratory – Promises, Procedures and Problems Michael E. Greenberg | Harvard Medical […]

Can fMRI reveal insights into addiction and treatments?

Many debilitating conditions like depression and addiction have biological signatures hidden in the brain well before symptoms appear.  What if brain scans could be used to detect these hidden signatures and determine the most optimal treatment for each individual? McGovern Investigator John Gabrieli is interested in this question and wrote about the use of imaging […]

Brain science in the Bolivian rainforest

Malinda McPherson is a graduate student in Josh McDermott‘s lab, studying how people hear pitch (how high or low a sound is) in both speech and music. To test the extent to which human audition varies across cultures, McPherson travels with the McDermott lab to Bolivia to study the Tsimane’ — a native Amazonian society […]

Single neurons can encode distinct landmarks

The organization of many neurons wired together in a complex circuit gives the brain its ability to perform powerful calculations. Work from the Harnett lab recently showed that even single neurons can process more information than previously thought, representing distinct variables at the subcellular level during behavior. McGovern Investigator Mark Harnett and postdoc Jakob Voigts […]

Shrinking CRISPR tools

Before CRISPR gene-editing tools can be used to treat brain disorders, scientists must find safe ways to deliver the tools to the brain. One promising method involves harnessing viruses that are benign, and replacing non-essential genetic cargo with therapeutic CRISPR tools. But there is limited room for additional tools in a vector already stuffed with […]

Two CRISPR scientists on the future of gene editing

As part of our Ask the Brain series, Martin Wienisch and Jonathan Wilde of the Feng lab look into the crystal ball to predict the future of CRISPR tech. _____ Where will CRISPR be in five years? Jonathan: We’ll definitely have more efficient, more precise, and safer editing tools. An immediate impact on human health […]

CRISPR: From toolkit to therapy

Think of the human body as a community of cells with specialized roles. Each cell carries the same blueprint, an array of genes comprising the genome, but different cell types have unique functions — immune cells fight invading bacteria, while neurons transmit information. But when something goes awry, the specialization of these cells becomes a […]

Controlling attention with brain waves

Having trouble paying attention? MIT neuroscientists may have a solution for you: Turn down your alpha brain waves. In a new study, the researchers found that people can enhance their attention by controlling their own alpha brain waves based on neurofeedback they receive as they perform a particular task. The study found that when subjects […]

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